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Inhibition of angiogenesis as a new therapeutic target in the treatment of lepromatous leprosy
Author(s) -
Mohamed ElKhalawany,
Shabaan,
Sultan Sultan,
FatmaM.A Al-Salam
Publication year - 2011
Publication title -
clinical cosmetic and investigational dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 35
ISSN - 1178-7015
DOI - 10.2147/ccid.s26200
Subject(s) - medicine , angiogenesis , immunostaining , cd31 , cd34 , neovascularization , leprosy , minocycline , group b , high power field , group a , lepromatous leprosy , cd68 , immunohistochemistry , pathology , gastroenterology , antibiotics , stem cell , biology , microbiology and biotechnology , genetics
Angiogenesis was suggested to have a significant role in the pathogenesis of leprosy. However, the benefit of inhibiting angiogenesis in lepromatous leprosy patients has not previously been studied. The purpose of this study was to evaluate angiogenesis in leprosy patients before and after treatment with multidrug therapy (MDT) with and without minocycline.

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