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Effect of extended-release niacin on hormone-sensitive lipase and lipoprotein lipase in patients with HIV-associated lipodystrophy syndrome
Author(s) -
Dominic C. Chow
Publication year - 2008
Publication title -
biologics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.948
H-Index - 38
eISSN - 1177-5491
pISSN - 1177-5475
DOI - 10.2147/btt.s3959
Subject(s) - lipodystrophy , lipoprotein lipase , lipase , niacin , medicine , endocrinology , human immunodeficiency virus (hiv) , hormone sensitive lipase , chemistry , enzyme , biochemistry , antiretroviral therapy , adipose tissue , immunology , viral load
HIV-associated lipodystrophy syndrome is strongly associated with antiretroviral treatment in patients with human immunodeficiency virus (HIV). Niacin is thought to affect hormone-sensitive lipase (HSL) and lipoprotein lipase (LPL) expression in peripheral and intra-abdominal fat (IAF).

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