Limited cross-reactivity of mouse monoclonal antibodies against Dengue virus capsid protein among four serotypes | Zendy

Tamaki Okabayashi | Zendy; Yamashita | Zendy; Masrinoul | Zendy; Punkum | Zendy; Pipattanaboon | Zendy; Chayanee Setthapramote | Zendy; Sasaski | Zendy; Mikiko Sasayama | Zendy; Kurosu | Zendy; Kazuyoshi Ikuta | Zendy; Ramasoota | Zendy; Noda | Zendy

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Limited cross-reactivity of mouse monoclonal antibodies against Dengue virus capsid protein among four serotypes

Author(s) -

Tamaki Okabayashi,

Yamashita,

Masrinoul,

Punkum,

Pipattanaboon,

Chayanee Setthapramote,

Sasaski,

Mikiko Sasayama,

Kurosu,

Kazuyoshi Ikuta,

Ramasoota,

Noda

Publication year - 2012

Publication title -

biologics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.948

H-Index - 38

eISSN - 1177-5491

pISSN - 1177-5475

DOI - 10.2147/btt.s37792

Subject(s) - capsid , virology , dengue virus , serotype , dengue fever , monoclonal antibody , biology , antibody , virus , immunology

Dengue illness is one of the important mosquito-borne viral diseases in tropical and subtropical regions. Four serotypes of dengue virus (DENV-1, DENV-2, DENV-3, and DENV-4) are classified in the Flavivirus genus of the family Flaviviridae. We prepared monoclonal antibodies against DENV capsid protein from mice immunized with DENV-2 and determined the cross-reactivity with each serotype of DENV and Japanese encephalitis virus.

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