Globular domain of adiponectin: promising target molecule for detection of atherosclerotic lesions | Zendy

Harald Mangge | Zendy; Saba-Lepek | Zendy; Haj-Yahya | Zendy; Eva Rohde | Zendy; Dirk Strunk | Zendy; Eleonore Fröhlich | Zendy; Ruth Prassl | Zendy; Gunter Almer | Zendy

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Globular domain of adiponectin: promising target molecule for detection of atherosclerotic lesions

Author(s) -

Harald Mangge,

Saba-Lepek,

Haj-Yahya,

Eva Rohde,

Dirk Strunk,

Eleonore Fröhlich,

Ruth Prassl,

Gunter Almer

Publication year - 2011

Publication title -

biologics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.948

H-Index - 38

eISSN - 1177-5491

pISSN - 1177-5475

DOI - 10.2147/btt.s22863

Subject(s) - adiponectin , globular cluster , molecule , domain (mathematical analysis) , chemistry , medicine , physics , mathematics , mathematical analysis , astrophysics , organic chemistry , galaxy , insulin , insulin resistance

Adiponectin, an adipocyte-specific plasma protein, has been shown to accumulate in injured endothelial cells during development of atherosclerotic lesions. In this study, we investigated the potential of different adiponectin subfractions with special emphasis on globular adiponectin (gAd) to recognize and visualize atherosclerotic lesions.

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