A simple method for assessing the strength of evidence for association at the level of the whole gene | Zendy

David Curtis | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

A simple method for assessing the strength of evidence for association at the level of the whole gene

Author(s) -

David Curtis

Publication year - 2008

Publication title -

advances and applications in bioinformatics and chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.223

H-Index - 15

ISSN - 1178-6949

DOI - 10.2147/aabc.s4095

Subject(s) - genetics , biology , gene , statistic , locus (genetics) , genetic association , computational biology , multiple comparisons problem , permutation (music) , association (psychology) , genotype , single nucleotide polymorphism , statistics , mathematics , psychology , psychotherapist , physics , acoustics

It is expected that different markers may show different patterns of association with different pathogenic variants within a given gene. It would be helpful to combine the evidence implicating association at the level of the whole gene rather than just for individual markers or haplotypes. Doing this is complicated by the fact that different markers do not represent independent sources of information.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research