Bioinformatics of Large-Scale Protein Interaction Networks | Zendy

Vincent Schächter | Zendy

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Bioinformatics of Large-Scale Protein Interaction Networks

Author(s) -

Vincent Schächter

Publication year - 2002

Publication title -

biotechniques

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.617

H-Index - 131

eISSN - 1940-9818

pISSN - 0736-6205

DOI - 10.2144/mar0203

Subject(s) - computer science , protein interaction networks , protein–protein interaction , reliability (semiconductor) , computational biology , annotation , scale (ratio) , systems biology , interaction network , artificial intelligence , biology , genetics , geography , power (physics) , physics , cartography , quantum mechanics , gene

We survey recent techniques for construction and prediction of large-scale protein interaction networks, focusing on computational processing steps. Special emphasis is placed on critical assessment of data completeness and reliability of the various approaches. Once built, protein interaction networks can be used for functional annotation or to generate higher-level biological hypotheses on pathways.

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