Open AccessMortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study
Author(s) -
Julia E. Wiedmeier,
Luke Mountjoy,
Matthew Buras,
Heidi E. Kosiorek,
Kyle Coppola,
Patricia M. Verona,
Curtiss B. Cook,
Nina J. Karlin
Publication year - 2021
Publication title -
future science oa
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 23
ISSN - 2056-5623
DOI - 10.2144/fsoa-2020-0117
Subject(s) - glycemic , medicine , myeloid leukemia , diabetes mellitus , leukemia , type 2 diabetes , gastroenterology , oncology , endocrinology
Aim: We examined the association between diabetes and survival in patients with acute and chronic myeloid leukemia and the association of leukemia with glycemic control. Patients & methods: Patients with leukemia with and without diabetes (2007–2015) were retrospectively identified and matched 1:1 (n = 70 per group). Overall survival was estimated by the Kaplan–Meier method. Hemoglobin A 1c and glucose levels the year after leukemia diagnosis were compared by mixed models. Results: Among 25 of 70 patients with diabetes, mean hemoglobin A 1c during the year after leukemia diagnosis was 6.8%. Kaplan–Meier-estimated 3-year survival was 46% for diabetes patients versus 45% for controls (p = 0.79). Conclusion: No associations were found between leukemia, diabetes, survival and glycemic control.