Human papillomavirus genotyping as a tool for cervical cancer prevention: from commercially available human papillomavirus DNA test to next-generation sequencing | Zendy

Tauana Christina Dias | Zendy; Adhemar LongattoFilho | Zendy; Nathália C. Campanella | Zendy

Open Access

Human papillomavirus genotyping as a tool for cervical cancer prevention: from commercially available human papillomavirus DNA test to next-generation sequencing

Author(s) -

Tauana Christina Dias,

Adhemar LongattoFilho,

Nathália C. Campanella

Publication year - 2020

Publication title -

future science oa

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 23

ISSN - 2056-5623

DOI - 10.2144/fsoa-2019-0159

Subject(s) - cervical cancer , genotyping , human papillomavirus , malignancy , carcinogenesis , cancer , oncology , biology , medicine , virology , cancer research , genetics , genotype , gene

The biological importance of human papillomavirus (HPV) in the field of medicine – related to cervical carcinogenesis – has been extensively reported in the last decades. For the first time, a direct correlation between cause and effect to explain a cancer development was completely achieved in medical research. Consequently, the Nobel Prize was awarded to HZ Hausen in 2008 for his efforts to understand the effects of persistent infection of oncogenic types of HPV and malignancy transformation. The aim of the present review was to summarize the principal elements of HPV characteristics and their importance in oncology.

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