Effect of ferric-carboxy Maltose on Oxygen Kinetics and Functional Status in Heart Failure Patients With Iron Deficiency | Zendy

S. Dhoot | Zendy; Sanjay Mittal | Zendy; Simar Pal Singh | Zendy; Vishal Patel | Zendy; Ravi R. Kasliwal | Zendy; Varshil Mehta | Zendy

Open Access

Effect of ferric-carboxy Maltose on Oxygen Kinetics and Functional Status in Heart Failure Patients With Iron Deficiency

Author(s) -

S. Dhoot,

Sanjay Mittal,

Simar Pal Singh,

Vishal Patel,

Ravi R. Kasliwal,

Varshil Mehta

Publication year - 2020

Publication title -

future science oa

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 23

ISSN - 2056-5623

DOI - 10.2144/fsoa-2019-0156

Subject(s) - heart failure , medicine , maltose , ejection fraction , anemia , randomized controlled trial , ferric , cardiology , iron deficiency , biochemistry , chemistry , organic chemistry , enzyme

There is a very high prevalence of iron deficiency anemia in patients with systolic heart failure. The present study is a prospective, parallel, 1:1 randomized controlled trial of intravenous ferric-carboxy maltose compared with standard of care in patients with heart failure. A total of 70 patients who presented to us with symptomatic chronic heart failure were included and randomly assigned to either groups (35 per group). Post 12 weeks, there were improvements noticed in peak VO 2 , New York Heart Association functional classification, 6-min walk test distance covered and reduction in Minnesota Living with Heart Failure Questionnaire score in the ferric-carboxy maltose as compared with standard of care group. However, no improvement in ejection fraction was noticed.

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