Molecularly Imprinted Polymers in Biological Applications | Zendy

Zahra El-Schich | Zendy; Yuecheng Zhang | Zendy; Marek Feith | Zendy; Sarah Beyer | Zendy; Louise Sternbæk | Zendy; Lars Ohlsson | Zendy; Maria M. Stollenwerk | Zendy; Anette Gjörloff Wingren | Zendy

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Molecularly Imprinted Polymers in Biological Applications

Author(s) -

Zahra El-Schich,

Yuecheng Zhang,

Marek Feith,

Sarah Beyer,

Louise Sternbæk,

Lars Ohlsson,

Maria M. Stollenwerk,

Anette Gjörloff Wingren

Publication year - 2020

Publication title -

biotechniques

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.617

H-Index - 131

eISSN - 1940-9818

pISSN - 0736-6205

DOI - 10.2144/btn-2020-0091

Subject(s) - molecularly imprinted polymer , glycan , molecular imprinting , nanotechnology , template , computational biology , chemistry , biology , materials science , biochemistry , glycoprotein , selectivity , catalysis

Molecularly imprinted polymers (MIPs) are currently widely used and further developed for biological applications. The MIP synthesis procedure is a key process, and a wide variety of protocols exist. The templates that are used for imprinting vary from the smallest glycosylated glycan structures or even amino acids to whole proteins or bacteria. The low cost, quick preparation, stability and reproducibility have been highlighted as advantages of MIPs. The biological applications utilizing MIPs discussed here include enzyme-linked assays, sensors, in vivo applications, drug delivery, cancer diagnostics and more. Indeed, there are numerous examples of how MIPs can be used as recognition elements similar to natural antibodies.

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