Open AccessModification of the enzyme mismatch cleavage method using T7 endonuclease I and silver staining
Author(s) -
Richard Mean,
Alkis Pierides,
Constantinos Deltas,
Michael Koptides
Publication year - 2004
Publication title -
biotechniques
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.617
H-Index - 131
eISSN - 1940-9818
pISSN - 0736-6205
DOI - 10.2144/04365bm01
Subject(s) - endonuclease , cleave , cleavage (geology) , dna , restriction enzyme , microbiology and biotechnology , enzyme , genetics , chemistry , biology , biochemistry , paleontology , fracture (geology)
The Silver Standard? Enzyme mismatch cleavage is a sensitive and accurate method for mutation detection. The approach entails bacteriophage resolvase cleavage of heteroduplex DNA formed by the anne...
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