Caspase-3 Colorimetric Assay

Apoptosis was originally described as a mechanism of controlled or physiological cell death (1). It is associated with the regulation of cellular homeostasis in organs and the elimination of damaged cells or of cells with deleterious reactivities from the host. Apoptosis is very common in tissues with intense hematopoietic activity (e.g. bone marrow and thymus) and in organs with high proliferative activity. Additionally, apoptosis has been implicated in the progression of a number of pathological conditions, including AIDS, cancer and autoimmune diseases (2, 3).