Mouse Behavior Tracker: An Economical Method for Tracking Behavior in Home Cages | Zendy

Sudheer Tungtur | Zendy; Natsuko Nishimune | Zendy; Jeff Radel | Zendy; Hiroshi Nishimune | Zendy

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Mouse Behavior Tracker: An Economical Method for Tracking Behavior in Home Cages

Author(s) -

Sudheer Tungtur,

Natsuko Nishimune,

Jeff Radel,

Hiroshi Nishimune

Publication year - 2017

Publication title -

biotechniques

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.617

H-Index - 131

eISSN - 1940-9818

pISSN - 0736-6205

DOI - 10.2144/000114607

Subject(s) - computer mouse , amyotrophic lateral sclerosis , tracking (education) , usb , computer science , simulation , software , real time computing , embedded system , human–computer interaction , psychology , medicine , operating system , pathology , pedagogy , disease

Analysis of mouse behavior often requires expensive equipment and transfer of the mice to new test environments, which could trigger confounding behavior alterations. Here, we describe a system for tracking mouse behavior in home cages using a low-cost USB webcam and free software (Fiji and wrMTrck). We demonstrate the effectiveness of this method by tracking differences in distance traveled, speed, and movement tracks between wild-type mice and amyotrophic lateral sclerosis (ALS) model mice (SOD1 G93A ).

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