Over the Rainbow: 25 Years of Confocal Imaging | Zendy

Steve Paddock | Zendy

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Over the Rainbow: 25 Years of Confocal Imaging

Author(s) -

Steve Paddock

Publication year - 2008

Publication title -

biotechniques

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.617

H-Index - 131

eISSN - 1940-9818

pISSN - 0736-6205

DOI - 10.2144/000112798

Subject(s) - confocal , instrumentation (computer programming) , microscope , laser scanning , confocal laser scanning microscopy , confocal microscopy , optics , laser , biology , computer science , physics , biophysics , operating system

Confocal microscopes have evolved over the past 25 years from the early stage scanning systems to a collection of sophisticated laser scanning systems designed for a range of biomedical applications. Major improvements to the photon efficiency of the instrumentation coupled with the development of novel fluorescent reporters have enabled multidimensional imaging of living cells and tissues.

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