Short Tandem Repeat Typing Technologies used in Human Identity Testing | Zendy

John M. Butler | Zendy

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Short Tandem Repeat Typing Technologies used in Human Identity Testing

Author(s) -

John M. Butler

Publication year - 2007

Publication title -

biotechniques

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.617

H-Index - 131

eISSN - 1940-9818

pISSN - 0736-6205

DOI - 10.2144/000112582

Subject(s) - str analysis , typing , str multiplex system , microsatellite , multiplex , multiplex polymerase chain reaction , biology , genetics , capillary electrophoresis , polymerase chain reaction , computational biology , tandem repeat , allele , microbiology and biotechnology , genome , gene

Short tandem repeat (STR) typing methods are widely used today for human identity testing applications including forensic DNA analysis. Following multiplex PCR amplification, DNA samples containing the length-variant STR alleles are typically separated by capillary electrophoresis and genotyped by comparison to an allelic ladder supplied with a commercial kit. This article offers a brief perspective on the technologies and issues involved in STR typing.

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