Innovative Proteomic Approaches for Cancer Biomarker Discovery | Zendy

Vítor M. Faça | Zendy; Alexei L. Krasnoselsky | Zendy; Samir Hanash | Zendy

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Innovative Proteomic Approaches for Cancer Biomarker Discovery

Author(s) -

Vítor M. Faça,

Alexei L. Krasnoselsky,

Samir Hanash

Publication year - 2007

Publication title -

biotechniques

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.617

H-Index - 131

eISSN - 1940-9818

pISSN - 0736-6205

DOI - 10.2144/000112541

Subject(s) - proteomics , biomarker discovery , computational biology , proteome , identification (biology) , cancer , biomarker , human proteome project , cancer biomarkers , biology , bioinformatics , genetics , gene , botany

Substantial technological advances in proteomics and related computational science have been made in the past few years. These advances overcome in part the complexity and heterogeneity of the human proteome, permitting quantitative analysis and identification of protein changes associated with tumor development. Here, we discuss some of these advances that are uncovering new cancer biomarkers that have potential to detect cancer at early and curable stages and address remaining challenges.

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