Miniaturized Spotter-Compatible Multicapillary Stamping Tool for Microarray Printing | Zendy

Alexei L. Drobyshev | Zendy; Nikolai N Verkhodanov | Zendy; А. С. Заседателев | Zendy

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Miniaturized Spotter-Compatible Multicapillary Stamping Tool for Microarray Printing

Author(s) -

Alexei L. Drobyshev,

Nikolai N Verkhodanov,

А. С. Заседателев

Publication year - 2007

Publication title -

biotechniques

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.617

H-Index - 131

eISSN - 1940-9818

pISSN - 0736-6205

DOI - 10.2144/000112535

Subject(s) - stamping , microarray , computational biology , computer science , materials science , biology , genetics , gene , gene expression , metallurgy

Novel microstamping tool for microarray printing is proposed. The tool is capable to spot up to 127 droplets of different solutions in single touch. It is easily compatible with commercially available microarray spotters. The tool is based on multichannel funnel with polypropylene capillaries inserted into its channels. Superior flexibility is achieved by ability to replace any printing capillary of the tool. As a practical implementation, hydrogel-based microarrays were stamped and successfully applied to identify the Mycobacterium tuberculosis drug resistance.

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