Serum D-Dimer Test Is Promising for the Diagnosis of Periprosthetic Joint Infection and Timing of Reimplantation | Zendy

Alisina Shahi | Zendy; Michael M. Kheir | Zendy; Majd Tarabichi | Zendy; Hamid Reza Seyyed Hosseinzadeh | Zendy; Timothy L. Tan | Zendy; Javad Parvizi | Zendy

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Serum D-Dimer Test Is Promising for the Diagnosis of Periprosthetic Joint Infection and Timing of Reimplantation

Author(s) -

Alisina Shahi,

Michael M. Kheir,

Majd Tarabichi,

Hamid Reza Seyyed Hosseinzadeh,

Timothy L. Tan,

Javad Parvizi

Publication year - 2017

Publication title -

journal of bone and joint surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.634

H-Index - 260

eISSN - 1058-2436

pISSN - 0021-9355

DOI - 10.2106/jbjs.16.01395

Subject(s) - medicine , periprosthetic , d dimer , erythrocyte sedimentation rate , gastroenterology , aseptic processing , prospective cohort study , c reactive protein , arthroplasty , cohort , surgery , inflammation

Despite the availability of a battery of tests, the diagnosis of periprosthetic joint infection (PJI) continues to be challenging. Serum D-dimer assessment is a widely available test that detects fibrinolytic activities that occur during infection. We hypothesized that patients with PJI may have a high level of circulating D-dimer and that the presence of a high level of serum D-dimer may be a sign of persistent infection in patients awaiting reimplantation.

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