The association of age-related macular degeneration and lens opacities in the aged. | Zendy

I Y Liu | Zendy; Lauren K. White | Zendy; Agnès Lacroix | Zendy

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The association of age-related macular degeneration and lens opacities in the aged.

Author(s) -

I Y Liu,

Lauren K. White,

Agnès Lacroix

Publication year - 1989

Publication title -

american journal of public health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.284

H-Index - 264

eISSN - 1541-0048

pISSN - 0090-0036

DOI - 10.2105/ajph.79.6.765

Subject(s) - macular degeneration , medicine , odds ratio , ophthalmology , logistic regression , risk factor , odds , eye disease , national health and nutrition examination survey , intraocular pressure , environmental health , population

Data from 3,087 persons age 45 or older in the National Health and Nutrition Survey, 1971-74, showed that subjects with lens opacifying disease had an increased odds for age-related macular degeneration (AMD) compared to those who had no lens opacities. The crude odds ratio for aphakic patients was 4.6 (95% CI = 2.5, 8.6). The association remained after controlling for age, sex, and systolic blood pressure (a common risk factor) in a logistic regression model. These data are consistent with the hypothesis that light-induced damage may contribute to both lens and retinal disease and suggest that cataract extraction without implantation of ultra-violet/blue light absorbing intraocular lens may place subjects at increased risk of AMD.

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