Open AccessTime of exposure and risk of HIV infection in homosexual partners of men with AIDS.
Author(s) -
Dennis Osmond,
Peter Bacchetti,
Richard E. Chaisson,
Thomas J. Kelly,
Robert R. Stempel,
James R. Carlson,
Andrew R. Moss
Publication year - 1988
Publication title -
american journal of public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.284
H-Index - 264
eISSN - 1541-0048
pISSN - 0090-0036
DOI - 10.2105/ajph.78.8.944
Subject(s) - odds ratio , medicine , anal intercourse , confidence interval , transmission (telecommunications) , demography , odds , sexual intercourse , sexual transmission , risk factor , homosexuality , human immunodeficiency virus (hiv) , immunology , psychology , population , men who have sex with men , environmental health , logistic regression , syphilis , microbicide , sociology , psychoanalysis , electrical engineering , engineering
We interviewed, and tested for HIV antibody, 117 homosexual men who had been regular sexual partners of men who developed acquired immunodeficiency syndrome (AIDS); 85 tested seropositive. Receptive anal intercourse with the index AIDS case and number of different sexual partners with whom subjects were anally receptive were both risk factors. Controlling for the number of partners with whom subjects were anally receptive, we found that the odds ratio of receptive anal intercourse with the case was infinite (95% confidence intervals, 3.3-infinity) if sexual contact continued up to or beyond the time of diagnosis, while the odds ratio was 1.0 (95% CI 0.3-3.2) if contact ceased before the case's AIDS diagnosis. Risk was not associated with the duration or frequency of contact. Our data suggest that the potential for sexual transmission from an HIV-infected person may be greater close to or after the onset of disease.