Severe local reactions to live measles virus vaccine following an immunization program. | Zendy

Harrison C. Stetler | Zendy; Robert D. Gens | Zendy; George R. Seastrom | Zendy

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Severe local reactions to live measles virus vaccine following an immunization program.

Author(s) -

Harrison C. Stetler,

Robert D. Gens,

George R. Seastrom

Publication year - 1983

Publication title -

american journal of public health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.284

H-Index - 264

eISSN - 1541-0048

pISSN - 0090-0036

DOI - 10.2105/ajph.73.8.899

Subject(s) - measles , medicine , measles vaccine , immunization , exact test , titer , measles virus , receipt , morbillivirus , test (biology) , virology , immunology , virus , vaccination , pediatrics , antibody , biology , world wide web , computer science , paleontology

A cluster of nine severe local reactions occurred in a Pennsylvania school district following a mass measles immunization program in February 1981. A case-control study showed that the nine cases had a statistically significant increased history of having received killed measles vaccine previously (p less than .001, Fisher's exact test) and a statistically significant higher geometric mean measles antibody titer (p less than .01, Student's t test) than controls, suggesting that previous receipt of killed measles vaccine was the underlying cause of these reactions.

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