Gastrointestinal diseases among relatives of patients with esophageal atresia with or without tracheoesophageal fistula | Zendy

Florian Zeck | Zendy; Heiko Reutter | Zendy

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Gastrointestinal diseases among relatives of patients with esophageal atresia with or without tracheoesophageal fistula

Author(s) -

Florian Zeck,

Heiko Reutter

Publication year - 2019

Publication title -

translational pediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.702

H-Index - 13

eISSN - 2224-4344

pISSN - 2224-4336

DOI - 10.21037/tp.2019.04.01

Subject(s) - medicine , tracheoesophageal fistula , atresia , esophagus , gastroenterology , carcinoma , gastrointestinal tract , achalasia

Several studies have identified genetic factors that are associated with the formation of isolated and non-isolated esophageal atresia with or without tracheoesophageal fistula (EA/TEF) in human and mice. Some of these genetic factors like FOXF1/Foxf1 are associated with Barrett syndrome, esophageal carcinoma or tumors of the gastrointestinal tract. Here, we investigated the prevalence of common gastrointestinal diseases among EA/TEF patients and their first- and second-degree relatives (parents and grandparents).

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