Open AccessDrug screening to target nuclear orphan receptor NR4A2 for cancer therapeutics
Author(s) -
Takefumi Komiya,
Satomi Yamamoto,
Anuradha Roy,
Peter R. McDonald,
Raymond P. Perez
Publication year - 2017
Publication title -
translational lung cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 41
eISSN - 2226-4477
pISSN - 2218-6751
DOI - 10.21037/tlcr.2017.07.02
Subject(s) - in vivo , nuclear receptor , cancer , drug discovery , pharmacology , cancer research , cancer cell , epidermal growth factor receptor , computational biology , medicine , biology , chemistry , biochemistry , gene , genetics , transcription factor
Our previous study suggested NR4A2, a subfamily member of orphan nuclear receptors, is essential for survival of human cancer cells such as mucoepidermoid carcinoma (MEC).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom