Open AccessGlycoprotein non-metastatic melanoma B expression after hepatic ischemia reperfusion and the effect of silibinin
Author(s) -
Adamantios Michalinos,
Alexandra Tsaroucha,
Maria Lambropoulou,
Dimitriοs Schizas,
Georgia Valsami,
Nikolaos Kostomitsopoulos,
M. Pitiakoudis,
Constantinos Simopoulos
Publication year - 2019
Publication title -
translational gastroenterology and hepatology
Language(s) - English
Resource type - Journals
ISSN - 2415-1289
DOI - 10.21037/tgh.2019.11.01
Subject(s) - silibinin , medicine , kidney , ischemia , inflammation , reperfusion injury , pharmacology , endocrinology , pathology
Hepatic I/R causes increase of GPNMB levels both in liver and kidney tissues, which may reflect tissue injury. Silibinin seems to act protectively on both liver and kidney, and can be potentially used as a therapeutic approach against hepatic I/R injury.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom