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Most oral squamous cell carcinoma (OSCC) cases have known associated risk factors including tobacco, alcohol, areca nut, etc. In addition to this, there has been an ongoing debate as to the etiology of oral cancer in patients without any known risk factors. In such cases, a microbial etiology has been hypothesized. Human papillomavirus (HPV) a proven risk factor for cervical and oropharyngeal cancer Original Article on Oral Pre-cancer and Cancer

Assessing the nature of the association of human papillomavirus in oral cancer with and without known risk factors