Increased serum level of interleukin-6 correlates with negative prognostic factors in extranodal NK/T-cell lymphoma | Zendy

Changqian Bao | Zendy; De Zhou | Zendy; Lixia Zhu | Zendy; Wenbin Qian | Zendy; Xiujin Ye | Zendy

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Increased serum level of interleukin-6 correlates with negative prognostic factors in extranodal NK/T-cell lymphoma

Author(s) -

Changqian Bao,

De Zhou,

Lixia Zhu,

Wenbin Qian,

Xiujin Ye

Publication year - 2020

Publication title -

translational cancer research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.254

H-Index - 30

eISSN - 2219-6803

pISSN - 2218-676X

DOI - 10.21037/tcr.2020.03.49

Subject(s) - medicine , t cell lymphoma , lymphoma , gastroenterology , proinflammatory cytokine , b symptoms , interleukin , stage (stratigraphy) , tumor necrosis factor alpha , immunology , oncology , cytokine , inflammation , biology , paleontology

Extranodal natural killer/T-cell lymphoma (ENKTL) is a highly aggressive malignant tumor with a poor prognosis (1). It is more common in Asia and Latin America than in Europe and North America (2), and accounts for 5% to 10% of malignant lymphomas in China (3). ENKTLs are histologically characterized by localized invasion, necrosis, and Epstein-Barr virus (EBV) infection of neoplastic cells. These tumors are confined to the nose and upper respiratory tract in 60% to 90% of patients (4), but may also occur outside the nasal cavity (e.g., in skin, testis, small intestine, and muscle) (2) or as a disseminated disease Original Article

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