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Extranodal natural killer/T-cell lymphoma (ENKTL) is a highly aggressive malignant tumor with a poor prognosis (1). It is more common in Asia and Latin America than in Europe and North America (2), and accounts for 5% to 10% of malignant lymphomas in China (3). ENKTLs are histologically characterized by localized invasion, necrosis, and Epstein-Barr virus (EBV) infection of neoplastic cells. These tumors are confined to the nose and upper respiratory tract in 60% to 90% of patients (4), but may also occur outside the nasal cavity (e.g., in skin, testis, small intestine, and muscle) (2) or as a disseminated disease Original Article

Increased serum level of interleukin-6 correlates with negative prognostic factors in extranodal NK/T-cell lymphoma