Data independent acquisition-mass spectrometry (DIA-MS)-based comprehensive profiling of bone metastatic cancers revealed molecular fingerprints to assist clinical classifications for bone metastasis of unknown primary (BMUP)

Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200240, China; Department of Orthopedic Oncology, Shanghai Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China Contributions: (I) Conception and design: W Yan, J Xiao; (II) Administrative support: W Yan, J Xiao; (III) Provision of study materials or patients: W Yan, J Xiao; (IV) Collection and assembly of data: S Chen, Z Zhou; (V) Data analysis and interpretation: X Ku, Y Xu; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Dr. Xin Ku. Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200240, China. Email: xinku@sjtu.edu.cn; Prof. Wei Yan. Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200240, China. Email: weiyan_99@uwalumni.com, weiyan@sjtu.edu.cn; Prof. Jianru Xiao. Department of Orthopedic Oncology, Shanghai Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China. Email: jianruxiao83@163.com.