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Additional treatment prolonged survival of pulmonary artery sarcoma after surgical resection
Author(s) -
Liwei Xu,
Weishan Lu,
Jianqiang Li,
Changchun Wang
Publication year - 2020
Publication title -
translational cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.254
H-Index - 30
eISSN - 2219-6803
pISSN - 2218-676X
DOI - 10.21037/tcr.2020.02.80
Subject(s) - medicine , hazard ratio , surgery , metastasis , confidence interval , sarcoma , adjuvant therapy , retrospective cohort study , survival rate , chemotherapy , cancer , pathology
Pulmonary artery sarcoma (PAS) is an extremely rare malignant tumor, that was first described by Mandelstamm in 1923 (1). Surgical intervention is the mainstay in the treatment for PAS, but the postoperative prognosis remains poor (2). The effect of adjuvant and/or neo-adjuvant chemotherapy and radiotherapy for PAS are controversial (3,4). However, PAS is very rare and there is currently no randomized controlled trial on adjuvant and/or neoadjuvant chemotherapy for PAS. In this study, to analyze the therapeutic effect of adjuvant therapy on postoperative survival time, we searched MEDLINE and EMBASE database, reviewed a total of 1397 articles published from 1932 to 2018, and selected 162 articles (275 cases). Original Article

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