The fatigue, sleep and physical activity in postoperative patients with pituitary adenoma: what we can do

Pituitary adenoma (PA) is the most common saddle-area tumor, which mainly occurs in young adults with prevalence of ranging from one in 865 adults to one in 2,688 adults (1). The growth of PA lead to endocrine dysfunction and central nervous compression, thereby causing related symptoms (2). Although PA is generally benign and it can be surgically removed, there are still some abnormal symptoms after surgery, which leads to the quality of life of surgical patients being damaged (3,4). Among postoperative symptoms, fatigue is a relatively widespread complaint (5). Previous studies (6) have reported that PA patients have significantly increased fatigue and decreased vitality compared with health populations. However, it’s been reported that there were no significant differences in fatigue scores between the four types of PA patients, namely, Cushing's disease, acromegaly, prolactinoma, and non-functional adenoma Original Article