Serum albumin levels and serum albumin-globulin ratio are associated with poor prognosis in glioblastoma | Zendy

Yalikun Kugeluke | Zendy; Tuerhong Tuersun | Zendy; Maiaitituersun Abudula | Zendy; Maijudan Tiheiran | Zendy; Qiang Fu | Zendy; Yisireyili Dilimulati | Zendy; Qingjiu Zhou | Zendy

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Serum albumin levels and serum albumin-globulin ratio are associated with poor prognosis in glioblastoma

Author(s) -

Yalikun Kugeluke,

Tuerhong Tuersun,

Maiaitituersun Abudula,

Maijudan Tiheiran,

Qiang Fu,

Yisireyili Dilimulati,

Qingjiu Zhou

Publication year - 2020

Publication title -

translational cancer research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.254

H-Index - 30

eISSN - 2219-6803

pISSN - 2218-676X

DOI - 10.21037/tcr.2020.01.57

Subject(s) - medicine , proportional hazards model , gastroenterology , albumin , logistic regression , serum albumin , adjuvant therapy , adjuvant , globulin , glioblastoma , medical record , clinical significance , oncology , cancer , cancer research

Glioma is the most common type of invasive malignant tumor in central nervous system (CNS), accounting for 65% of primary intracranial tumors (1,2). In 2016, World Health Organization (WHO) classified glioma into grade I-IV histologically according to the degree of malignancy. Grade IV is glioblastoma (GBM), which is highly invasive with poor prognosis (3). Despite the complete resection of GBM plus postoperative radiotherapy and chemotherapy, the median PFS and OS is not optimistic (4). Although certain prognostic factors for GBM have been reported (5,6), the guiding function to the current treatment is limited, which warranted the new prognostic factors to be constantly Original Article

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