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Potential of microRNA expression profile in predicting renal impairment risk in multiple myeloma patients
Author(s) -
Daijin Ren,
Yuwen Cai,
Gaosi Xu
Publication year - 2020
Publication title -
translational cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.254
H-Index - 30
eISSN - 2219-6803
pISSN - 2218-676X
DOI - 10.21037/tcr.2020.01.41
Subject(s) - microrna , multiple myeloma , receiver operating characteristic , medicine , real time polymerase chain reaction , area under the curve , area under curve , microarray , gastroenterology , microbiology and biotechnology , oncology , gene expression , biology , gene , genetics , pharmacokinetics
Multiple myeloma (MM), as a hematological malignancy featured by clonal proliferation of malignant plasma cells which accounts for around 1% of neoplastic diseases and 13% of hematologic malignancies, commonly accompanied with severe symptoms such as renal impairment (RI), extensive skeletal destruction, infections, anemia, hypercalcemia and so on (1). Among these complications, RI occurs in 20–50% MM patients worldwide, while in Original Article

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