Clinical characteristics and treatments of large cell lung carcinoma: a retrospective study using SEER data | Zendy

Qidong Tai | Zendy; Lei Zhang | Zendy; Xuefei Hu | Zendy

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Clinical characteristics and treatments of large cell lung carcinoma: a retrospective study using SEER data

Author(s) -

Qidong Tai,

Lei Zhang,

Xuefei Hu

Publication year - 2020

Publication title -

translational cancer research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.254

H-Index - 30

eISSN - 2219-6803

pISSN - 2218-676X

DOI - 10.21037/tcr.2020.01.40

Subject(s) - medicine , nomogram , stage (stratigraphy) , proportional hazards model , oncology , chemotherapy , epidemiology , multivariate analysis , radiation therapy , marital status , lung cancer , surveillance, epidemiology, and end results , univariate analysis , cancer registry , population , paleontology , environmental health , biology

Lung cancer is the most common malignant tumor in the world and has the highest fatality rate (1). It consists of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Histologically, NSCLC can be further classified as adenocarcinoma, squamous cell carcinoma and large cell carcinoma with or without neuroendocrine features. In NSCLC, according to cohort demographics and classification scheme, large cell lung cancer (LCLC) only accounts for 9% of all cases and often has poor differentiation and prognosis (2-5). Based on the WHO lung cancer classification (6), LCLC is defined as an undifferentiated non-small cell Original Article

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