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Department of Interventional Radiology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China Contributions: (I) Conception and design: YH Huang, N Li; (II) Administrative support: YH Huang; (III) Provision of study materials or patients: N Li; (IV) Collection and assembly of data: N Li; (V) Data analysis and interpretation: YH Huang, N Li; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Dr. Yong-Hui Huang; Dr. Nan Li. Department of Interventional Radiology, the First Affiliated Hospital, Sun Yat-sen University, 58th Zhongshan Road II, Guangzhou 510080, China. Email: cir.huangyonghui@vip.163.com; zsylinan@163.com.

The suppressing effects of VEGF-mediated angiogenesis at different administration sequences of apatinib and transarterial embolization in vivo