Open AccessFOXO3/TRIM22 axis abated the antitumor effect of gemcitabine in non-small cell lung cancer via autophagy induction
Author(s) -
Yang Wang,
Hengxing Liang,
Chunmin Zhang,
Min Zou,
Bi-bo Zou,
Wei Wei,
Wen Hu
Publication year - 2020
Publication title -
translational cancer research
Language(s) - English
Resource type - Journals
eISSN - 2219-6803
pISSN - 2218-676X
DOI - 10.21037/tcr.2019.12.33
Subject(s) - propidium iodide , a549 cell , gemcitabine , cancer research , autophagy , apoptosis , cell culture , lung cancer , downregulation and upregulation , medicine , oncology , biology , programmed cell death , cancer , gene , biochemistry , genetics
Department of Pathology, Department of Thoracic Surgery, the Second Xiangya Hospital of Central South University, Changsha 410000, China; Institute of Foreign Languages, Central South University, Changsha 410000, China; Institute of Transformation Medicine Affiliated to Hunan Yearth Biotechnology Co., Ltd. Changsha 410000, China Contributions: (I) Conception and design: W Hu; (II) Administrative support: Y Wang; (III) Provision of study materials or patients: HX Liang; (IV) Collection and assembly of data: M Zou, BB Zou; (V) Data analysis and interpretation: M Zou, BB Zou; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Wen Hu. Department of Thoracic Surgery, the Second Xiangya Hospital of Central South University, No. 139 of Renmin Road, Changsha 410000, China. Email: huwen@csu.edu.cn.
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