Open AccessA mechanism for the tissue specificity in BAP1 cancer syndrome
Author(s) -
Yuichi Machida
Publication year - 2019
Publication title -
translational cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.254
H-Index - 30
eISSN - 2219-6803
pISSN - 2218-676X
DOI - 10.21037/tcr.2019.06.41
Subject(s) - mechanism (biology) , cancer , bap1 , medicine , biology , cancer research , computational biology , philosophy , epistemology
Cancer predisposition syndromes are caused by inherited mutations in tumor suppressor genes. Remarkably, despite the presence of the faulty tumor suppressor gene in virtually every cell in the body, individuals with a cancer predisposition syndrome develop tumors in specific organs but not others.
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