5-FU blocks shuttling of HuR mediated by PKCδ in gastric cancer cells

Department of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China; Department of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Institude of Mental Healthy, The Affiliated Kangning Hospital of Wenzhou Medical University, Wenzhou, China; Department of Pediatric Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Department of oncology, The Affiliated Hospital of Jiangnan University, Wuxi, China; Department of Burn, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China Contributions: (I) Conception and design: D Hua, Z Hong, W Wu, S Xu; (II) Administrative support: C Chen, X Chen; (III) Provision of study materials or patients: W Wu, S Xu, K Guan, W Zhang, Z Hong; (IV) Collection and assembly of data: D Hua, Z Hong, W Wu, S Xu; (V) Data analysis and interpretation: D Hua, Z Hong, W Wu; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. These authors contributed equally to this work. Correspondence to: Dong Hua. Department of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China. Email: HUADong@csco.org.cn; Zipu Hong. Department of Burn, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China. Email: hzp120119@163.com.