Different prognosis by subtype in the early mucinous breast cancer: a SEER population-based analysis | Zendy

Weibin Lian | Zendy; Juanjuan Zheng | Zendy; Debo Chen | Zendy

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Different prognosis by subtype in the early mucinous breast cancer: a SEER population-based analysis

Author(s) -

Weibin Lian,

Juanjuan Zheng,

Debo Chen

Publication year - 2020

Publication title -

translational cancer research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.254

H-Index - 30

eISSN - 2219-6803

pISSN - 2218-676X

DOI - 10.21037/tcr-20-1237

Subject(s) - medicine , breast cancer , oncology , male breast cancer , estrogen receptor , proportional hazards model , gynecology , progesterone receptor , population , histology , cancer , stage (stratigraphy) , epidemiology , gastroenterology , biology , paleontology , environmental health

Mucinous breast cancer (MBC) is a rare histological type, which was reported to account for 1% to 7% of all invasive breast cancer (1-3). Previous studies suggested that MBC differs from other histological breast cancer types and has favorable prognosis (90% overall survival and 96% breast cancer-special survival at 10 years) (4,5). MBC was associated with a smaller tumor size, lower rates of nodal involvement, a high expression of hormone receptors (HR) and more human epidermal growth factor receptor 2 (HER2)-negative than infiltrating ductal carcinoma (IDC) (2,6). What is confusing is that whether the good prognosis of MBC is due to good biological behavior or just as an independent prognostic factor. However, some previous reports have biased results due to the limitation of study population and insufficient follow-up time. Additionally, most of the current treatment guidelines for MBC are Original Article

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