Bladder attack: transient bladder ischemia leads to a reversible decrease in detrusor compliance | Zendy

Andrew Tracey | Zendy; Uzoma A. Anele | Zendy; Randy Vince | Zendy; John E. Speich | Zendy; Adam P. Klausner | Zendy; Paul H. Ratz | Zendy

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Bladder attack: transient bladder ischemia leads to a reversible decrease in detrusor compliance

Author(s) -

Andrew Tracey,

Uzoma A. Anele,

Randy Vince,

John E. Speich,

Adam P. Klausner,

Paul H. Ratz

Publication year - 2019

Publication title -

translational andrology and urology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.721

H-Index - 27

eISSN - 2223-4691

pISSN - 2223-4683

DOI - 10.21037/tau.2019.11.12

Subject(s) - ischemia , ex vivo , detrusor muscle , carbachol , urinary bladder , hypoxia (environmental) , in vivo , medicine , perfusion , contraction (grammar) , atropine , urology , anesthesia , chemistry , endocrinology , stimulation , biology , oxygen , microbiology and biotechnology , organic chemistry

The deleterious effects of chronic ischemia on bladder function have been extensively studied; however, evaluation and characterization of the effects of acute ischemia and hypoxia are lacking. The present study examined pig and human detrusor smooth muscle (DSM) strips, in combination with an isolated perfused working pig bladder model to evaluate the relationship between transient ischemia and bladder function.

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