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Consensus approach for 3D joint space width of metacarpophalangeal joints of rheumatoid arthritis patients using high-resolution peripheral quantitative computed tomography
Author(s) -
Kathryn S. Stok,
Andrew J. Burghardt,
Stéphanie Boutroy,
M. Peters,
Sarah L. Manske,
Vincent A. Stadelmann,
Nicolas Vilayphiou,
Joop P. van den Bergh,
Piet Geusens,
Xiaojuan Li,
Hubert Marotte,
Bert van Rietbergen,
Steven K. Boyd,
Cheryl Barnabé
Publication year - 2020
Publication title -
quantitative imaging in medicine and surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 21
eISSN - 2223-4292
pISSN - 2223-4306
DOI - 10.21037/qims.2019.12.11
Subject(s) - quantitative computed tomography , reproducibility , metacarpophalangeal joint , computed tomography , computer science , joint (building) , medicine , nuclear medicine , radiology , mathematics , statistics , surgery , pathology , osteoporosis , bone mineral , architectural engineering , thumb , engineering
Joint space assessment for rheumatoid arthritis (RA) by ordinal conventional radiographic scales is susceptible to floor and ceiling effects. High-resolution peripheral quantitative computed tomography (HR-pQCT) provides superior resolution, and may detect earlier changes. The goal of this work was to compare existing 3D methods to calculate joint space width (JSW) metrics in human metacarpophalangeal (MCP) joints with HR-pQCT and reach consensus for future studies. Using the consensus method, we established reproducibility with repositioning as well as feasibility for use in second-generation HR-pQCT scanners.

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