SPIO-loaded nanostructured lipid carriers as liver-targeted molecular T2-weighted MRI contrast agent | Zendy

Xiuliang Zhu | Zendy; XueYing Deng | Zendy; Chenying Lu | Zendy; Ying Chen | Zendy; Liyong Jie | Zendy; Qian Zhang | Zendy; Wei Li | Zendy; Zuhua Wang | Zendy; YongZhong Du | Zendy; RiSheng Yu | Zendy

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SPIO-loaded nanostructured lipid carriers as liver-targeted molecular T2-weighted MRI contrast agent

Author(s) -

Xiuliang Zhu,

XueYing Deng,

Chenying Lu,

Ying Chen,

Liyong Jie,

Qian Zhang,

Wei Li,

Zuhua Wang,

YongZhong Du,

RiSheng Yu

Publication year - 2018

Publication title -

quantitative imaging in medicine and surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.766

H-Index - 21

eISSN - 2223-4292

pISSN - 2223-4306

DOI - 10.21037/qims.2018.09.03

Subject(s) - in vivo , in vitro , cytotoxicity , magnetic resonance imaging , flow cytometry , hepatocyte , mri contrast agent , chemistry , biocompatibility , confocal , in vitro toxicology , biophysics , pathology , microbiology and biotechnology , medicine , biochemistry , biology , radiology , geometry , mathematics , organic chemistry

Superparamagnetic iron oxide (SPIO) acts as a negative contrast agent in magnetic resonance imaging (MRI), and is widely used in clinical applications, including the diagnosis of hepatic diseases. Hepatocyte-targeted magnetic resonance contrast agents (MRCAs) can provide useful information for evaluating hepatic diseases. We prepared targeted magnetic nanostructured lipid carriers (MNLCs) to enhance the hepatocytes targeting efficiency.

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