Rapid quantification of global brain volumetry and relaxometry in patients with multiple sclerosis using synthetic magnetic resonance imaging | Zendy

Jibin Cao | Zendy; Xiaohan Xu | Zendy; Jingyi Zhu | Zendy; PuYeh Wu | Zendy; Huize Pang | Zendy; Guoguang Fan | Zendy; Lingling Cui | Zendy

Open Access

Rapid quantification of global brain volumetry and relaxometry in patients with multiple sclerosis using synthetic magnetic resonance imaging

Author(s) -

Jibin Cao,

Xiaohan Xu,

Jingyi Zhu,

PuYeh Wu,

Huize Pang,

Guoguang Fan,

Lingling Cui

Publication year - 2022

Publication title -

quantitative imaging in medicine and surgery

Language(s) - English

Resource type - Journals

eISSN - 2223-4292

pISSN - 2223-4306

DOI - 10.21037/qims-21-970

Subject(s) - relaxometry , multiple sclerosis , medicine , magnetic resonance imaging , expanded disability status scale , white matter , brain size , nuclear medicine , myelin , imaging biomarker , pathology , radiology , central nervous system , immunology , spin echo

Early pathologic studies have reported that focal areas of gray lesions in the cortex and other gray matter (GM) regions are important in multiple sclerosis (MS) patients. Quantitative magnetic resonance imaging (qMRI) can provide more specific insight into the disease process, progression, and therapeutic response of MS. The purpose of this study was to quantitatively assess the changes of global GM volumetry and relaxometry information simultaneously in MS patients using synthetic MRI.

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