Development and evaluation of a T1 standard brain template for Alzheimer disease | Zendy

XiaoYi Guo | Zendy; Yunjung Chang | Zendy; Yehee Kim | Zendy; Hak Young Rhee | Zendy; Ah Rang Cho | Zendy; Soonchan Park | Zendy; ChangWoo Ryu | Zendy; Jin San Lee | Zendy; Kyung Mi Lee | Zendy; WonChul Shin | Zendy; KeyChung Park | Zendy; Eui Jong Kim | Zendy; GeonHo Jahng | Zendy

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Development and evaluation of a T1 standard brain template for Alzheimer disease

Author(s) -

XiaoYi Guo,

Yunjung Chang,

Yehee Kim,

Hak Young Rhee,

Ah Rang Cho,

Soonchan Park,

ChangWoo Ryu,

Jin San Lee,

Kyung Mi Lee,

WonChul Shin,

KeyChung Park,

Eui Jong Kim,

GeonHo Jahng

Publication year - 2021

Publication title -

quantitative imaging in medicine and surgery

Language(s) - English

Resource type - Journals

eISSN - 2223-4292

pISSN - 2223-4306

DOI - 10.21037/qims-20-710

Subject(s) - voxel , white matter , cognitive impairment , brain tissue , medicine , hippocampus , disease , nuclear medicine , pathology , psychology , audiology , magnetic resonance imaging , radiology

Patients with Alzheimer disease (AD) and mild cognitive impairment (MCI) have high variability in brain tissue loss, making it difficult to use a disease-specific standard brain template. The objective of this study was to develop an AD-specific three-dimensional (3D) T1 brain tissue template and to evaluate the characteristics of the populations used to form the template.

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