Review on experimental study and clinical application of low- intensity pulsed ultrasound in inflammation | Zendy

Maosheng Xu | Zendy; Liang Wang | Zendy; Senmin Wu | Zendy; Yanyan Dong | Zendy; Chen Xiu | Zendy; Shijia Wang | Zendy; Xiuyun Li | Zendy; Chunpeng Zou | Zendy

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Review on experimental study and clinical application of low- intensity pulsed ultrasound in inflammation

Author(s) -

Maosheng Xu,

Liang Wang,

Senmin Wu,

Yanyan Dong,

Chen Xiu,

Shijia Wang,

Xiuyun Li,

Chunpeng Zou

Publication year - 2020

Publication title -

quantitative imaging in medicine and surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.766

H-Index - 21

eISSN - 2223-4292

pISSN - 2223-4306

DOI - 10.21037/qims-20-680

Subject(s) - low intensity pulsed ultrasound , inflammation , medicine , clinical trial , bioinformatics , ultrasound , immunology , pathology , therapeutic ultrasound , radiology , biology

Low-intensity pulsed ultrasound (LIPUS), as physical therapy, is widely used in both research and clinical settings. It induces multiple bioeffects, such as alleviating pain, promoting tissue repair, and shortening disease duration. LIPUS can also mediate inflammation. This paper reviews the application of LIPUS in inflammation and discusses the underlying mechanism. In basic experiments, LIPUS can regulate inflammatory responses at the cellular level by affecting some signaling pathways. In a clinical trial, LIPUS has been shown to alleviate inflammatory responses efficiently. As a cheap, safe, and convenient physical method, LIPUS is promising as anti-inflammatory therapy.

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