Open AccessAssessment of liver fibrosis with liver and spleen magnetic resonance elastography, serum markers in chronic liver disease
Author(s) -
Xiaopei Wang,
Yu Wang,
Hong Ma,
Han Wang,
Dawei Yang,
Xinyan Zhao,
Erhu Jin,
Zhenghan Yang
Publication year - 2020
Publication title -
quantitative imaging in medicine and surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 21
eISSN - 2223-4292
pISSN - 2223-4306
DOI - 10.21037/qims-19-849
Subject(s) - liver fibrosis , spleen , elastography , magnetic resonance elastography , pathology , medicine , magnetic resonance imaging , chronic liver disease , liver disease , disease , transient elastography , gastroenterology , fibrosis , radiology , ultrasound , cirrhosis
The accurate assessment of liver fibrosis is essential for patients with chronic liver disease. A liver biopsy is an invasive procedure that has many potential defects and complications. Therefore, noninvasive assessment techniques are of considerable value for clinical diagnosis. Liver and spleen magnetic resonance elastography (MRE) and serum markers have been proposed for quantitative and noninvasive assessment of liver fibrosis. This study aims to compare the diagnostic performance of liver and spleen stiffness measured by MRE, fibrosis index based on the 4 factors (FIB-4), aspartate aminotransferase-to-platelet ratio index (APRI), and their combined models for staging hepatic fibrosis.
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