Serum alpha 1-antitrypsin predicts severe acute kidney injury after cardiac surgery | Zendy

Songlin Du | Zendy; Jianwei Tian | Zendy; Zhiwen Xiao | Zendy; Zhiwen Luo | Zendy; Tong Lin | Zendy; Shaoyi Zheng | Zendy; Jun Ai | Zendy

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Serum alpha 1-antitrypsin predicts severe acute kidney injury after cardiac surgery

Author(s) -

Songlin Du,

Jianwei Tian,

Zhiwen Xiao,

Zhiwen Luo,

Tong Lin,

Shaoyi Zheng,

Jun Ai

Publication year - 2019

Publication title -

journal of thoracic disease

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 0.682

H-Index - 60

eISSN - 2077-6624

pISSN - 2072-1439

DOI - 10.21037/jtd.2019.12.17

Subject(s) - medicine , acute kidney injury , quartile , perioperative , creatinine , cardiac surgery , prospective cohort study , kidney disease , intensive care unit , cardiopulmonary bypass , surgery , confidence interval

Human alpha 1-antitrypsin (A1AT) is involved in the pathophysiological process underlying ischemic acute kidney injury (AKI). To test the hypothesis that serum A1AT (sA1AT) is a predictor for severe AKI after cardiopulmonary bypass (CPB), we conducted a prospective cohort study in 201 patients undergoing cardiac surgery.

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