Retrospective immunohistological study of autopsied lungs in patients with acute exacerbation of interstitial pneumonia managed with extracorporeal membrane oxygenation | Zendy

Yoshiko Kida | Zendy; Shinichiro Ohshimo | Zendy; Michihito Kyo | Zendy; Koji Hosokawa | Zendy; Vishwa Jeet Amatya | Zendy; Yukio Takeshima | Zendy; Nobuaki Shime | Zendy

Open Access

Retrospective immunohistological study of autopsied lungs in patients with acute exacerbation of interstitial pneumonia managed with extracorporeal membrane oxygenation

Author(s) -

Yoshiko Kida,

Shinichiro Ohshimo,

Michihito Kyo,

Koji Hosokawa,

Vishwa Jeet Amatya,

Yukio Takeshima,

Nobuaki Shime

Publication year - 2019

Publication title -

journal of thoracic disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.682

H-Index - 60

eISSN - 2077-6624

pISSN - 2072-1439

DOI - 10.21037/jtd.2019.11.09

Subject(s) - medicine , mechanical ventilation , extracorporeal membrane oxygenation , ards , intensive care unit , pneumonia , anesthesia , extracorporeal , ventilation (architecture) , exacerbation , oxygenation , lung , mechanical engineering , engineering

Acute exacerbation of interstitial pneumonia (AE-IP) is a life-threatening pulmonary condition that involves various pathogeneses. In patients with AE-IP who need mechanical ventilation with high driving pressure and oxygen concentration, veno-venous extracorporeal membrane oxygenation (V-V ECMO) may diminish alveolar epithelial damage by decreasing ventilator settings. The pathophysiological benefit of this therapeutic option is not well investigated.

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