Potential clinical utility of multiple target quantitative polymerase chain reaction (qPCR) array to detect microbial pathogens in patients with chronic obstructive pulmonary disease (COPD) | Zendy

Hannah E. O’Farrell | Zendy; Janet G. Shaw | Zendy; Felicia Goh | Zendy; Rayleen Bowman | Zendy; Kwun M. Fong | Zendy; Lutz Krause | Zendy; Ian A. Yang | Zendy

Open Access

Potential clinical utility of multiple target quantitative polymerase chain reaction (qPCR) array to detect microbial pathogens in patients with chronic obstructive pulmonary disease (COPD)

Author(s) -

Hannah E. O’Farrell,

Janet G. Shaw,

Felicia Goh,

Rayleen Bowman,

Kwun M. Fong,

Lutz Krause,

Ian A. Yang

Publication year - 2019

Publication title -

journal of thoracic disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.682

H-Index - 60

eISSN - 2077-6624

pISSN - 2072-1439

DOI - 10.21037/jtd.2019.10.39

Subject(s) - sputum , microbiology and biotechnology , 16s ribosomal rna , pseudomonas aeruginosa , polymerase chain reaction , microbiological culture , ribosomal rna , sputum culture , copd , streptococcus pneumoniae , exacerbation , haemophilus influenzae , biology , real time polymerase chain reaction , medicine , bacteria , antibiotics , gene , immunology , pathology , tuberculosis , genetics

Culture-independent methods such as quantitative polymerase chain reaction (qPCR) are more sensitive for detecting pathogens than conventional culture. This study aimed to test the clinical potential of a multiple target qPCR array in identifying sputum pathogens, compared to traditional culture.

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