Dysphagia predict the response to second cycle neoadjuvant chemotherapy in first cycle no response esophageal carcinoma | Zendy

Yan Zheng | Zendy; Yin Li | Zendy; Jianjun Qin | Zendy; Wenqun Xing | Zendy; Xianben Liu | Zendy; Haibo Sun | Zendy; Xiankai Chen | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Dysphagia predict the response to second cycle neoadjuvant chemotherapy in first cycle no response esophageal carcinoma

Author(s) -

Yan Zheng,

Yin Li,

Jianjun Qin,

Wenqun Xing,

Xianben Liu,

Haibo Sun,

Xiankai Chen

Publication year - 2019

Publication title -

journal of thoracic disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.682

H-Index - 60

eISSN - 2077-6624

pISSN - 2072-1439

DOI - 10.21037/jtd.2019.10.02

Subject(s) - medicine , dysphagia , esophageal cancer , odds ratio , confidence interval , progressive disease , univariate analysis , oncology , response evaluation criteria in solid tumors , multivariate analysis , gastroenterology , surgery , cancer , chemotherapy

After the first-cycle of neoadjuvant chemotherapy (NAC), many patients with esophageal squamous cell carcinoma (ESCC) experience a stable disease (SD)/progressive disease (PD) response. Clinically, SD patients are recommended to receive a second cycle of NAC, and PD patients are recommended to undergo surgery if possible. However, we found some PD tumors shrank after a second-cycle of NAC. Some first-cycle SD patients may develop PD after second-cycle NAC and lose the chance of surgery. Thus, how to predict the response to second-cycle NAC for first-cycle SD/PD patients is important for clinical practice.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research