Elevation of pulmonary CD163+ and CD204+ macrophages is associated with the clinical course of idiopathic pulmonary fibrosis patients
Author(s) -
Takashi Nouno,
Masaki Okamoto,
Koji Ohnishi,
Shinjiro Kaieda,
Masaki Tominaga,
Yoshiaki Zaizen,
Masao Ichiki,
Seiya Momosaki,
Masayuki Nakamura,
Kiminori Fujimoto,
Junya Fukuoka,
Shigeki Shimizu,
Yoshihiro Komohara,
Tomoaki Hoshino
Publication year - 2019
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2019.09.03
Subject(s) - cd68 , cd163 , idiopathic pulmonary fibrosis , medicine , pulmonary fibrosis , pathology , macrophage , lung , lung biopsy , fibrosis , immunology , immunohistochemistry , biopsy , biology , in vitro , biochemistry
M2-like/repair macrophages are thought to contribute to fibrotic process of idiopathic pulmonary fibrosis (IPF). We analyzed the association between pulmonary accumulation of M2-like macrophages and survival in IPF patients.
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