Evaluation of high-risk pulmonary nodules and pathologic correlation in patients enrolled in a low-dose computed tomography (LDCT) program

This is one of the few studies that examined the correlation of lung-RADS risk stratification and histopathologic nature of nodules. In addition to demonstrating the merits of the low-dose CT screening program, our study has demonstrated, amongst the large number of patients, very low rates of migration from low lung-RADS classification to a higher risk category, the finding of more advanced stages of malignancies, and a preponderance of adenocarcinoma within the eight malignancies found.